Diabetes History Fun

I liked Paul's question a lot. OK How about what I think is a wonderful story (true) Eva Saxi? Hint: Love

Cheating Destiny by James S Hirsch--WW2-insulin could no longer be imported where Eva was.Her husband had to find ways to help her survive.Where was she ?

I haven't read that book... yet.  What are some of the details of this story?

OK.  Here's another tough one.  Who is this guy and what does he have to do with diabetes?

Hint:  The yearf was 1879.

 

[quote user="meme"]

Cheating Destiny by James S Hirsch--WW2-insulin could no longer be imported where Eva was.Her husband had to find ways to help her survive.Where was she ?

[/quote]

 

She and her husband were in China. He taught himself (he was an Eng.) how to make insulin from large animals, mostly Water Buffalo. He promised to take care of his wife no matter what because he loved her!!!!!! I have a PDF of the story from ADA if anyone would like

 

[quote user="Paul Glantzman"]

OK.  Here's another tough one.  Who is this guy and what does he have to do with diabetes?

Hey really good one. Ira Remsen and a student Constantin Fahlberg found Saccharin.

Hint:  The yearf was 1879.

 

[/quote]

 

Here's one for you Paul. NPH had a change from other insulins. What was added and what is the source???

[quote user="Keith221"]

[quote user="meme"]

Cheating Destiny by James S Hirsch--WW2-insulin could no longer be imported where Eva was.Her husband had to find ways to help her survive.Where was she ?

[/quote]

 

She and her husband were in China. He taught himself (he was an Eng.) how to make insulin from large animals, mostly Water Buffalo. He promised to take care of his wife no matter what because he loved her!!!!!! I have a PDF of the story from ADA if anyone would like

 

[/quote]

 

Keith,,

Please email it to me:  paulg765@gmail.com

Next time I find myself without health insurance, I'll see if I can get my hands on some local Water Buffalo.  (Probably a lot less of a hassle than dealing with the insurance companies :)

Back to the Saccharin story, here is one accounting from Wikipedia:

In 1879 he made the greatest discovery of his career by accident. When he ate rolls at dinner after a long day in the lab researching coal tar derivatives, he noticed that the rolls tasted initially sweet but then bitter. Since his wife tasted nothing strange about the rolls, Remsen tasted his fingers and noticed that the bitter taste was probably from one of the chemicals in his lab. The next day at his lab he tasted the chemicals that he had been working with the previous day and discovered that it was the oxidation of o-toluenesulfonamide he had tasted the previous evening. He named the substance saccharin.  Constantin Fahlberg published their finding in 1880. Later Remsen became angry after Fahlberg patented saccharin, claiming that he had discovered saccharin. and he and his research partner

 

There are 2 morals to this story:

  1. Under no circumstances should you ever trust a business partner.
  2. And definitely..., you should NEVER wash your hands before dinner.

 

[quote user="Paul Glantzman"]

Back to the Saccharin story, here is one accounting from Wikipedia:

In 1879 he made the greatest discovery of his career by accident. When he ate rolls at dinner after a long day in the lab researching coal tar derivatives, he noticed that the rolls tasted initially sweet but then bitter. Since his wife tasted nothing strange about the rolls, Remsen tasted his fingers and noticed that the bitter taste was probably from one of the chemicals in his lab. The next day at his lab he tasted the chemicals that he had been working with the previous day and discovered that it was the oxidation of o-toluenesulfonamide he had tasted the previous evening. He named the substance saccharin.  Constantin Fahlberg published their finding in 1880. Later Remsen became angry after Fahlberg patented saccharin, claiming that he had discovered saccharin. and he and his research partner

 

There are 2 morals to this story:

  1. Under no circumstances should you ever trust a business partner.
  2. And definitely..., you should NEVER wash your hands before dinner.

 

[/quote]

Oh, yeah. I go into my science lab and go around tasting all of the chemicals. Because that's the smart, safe thing to do. =P

[quote user="Keith221"]

Here's one for you Paul. NPH had a change from other insulins. What was added and what is the source???

[/quote]

I actually remembered having read about this one.  The "P" in NPH stands for "Protamine," which is the unique ingredient which slows down the onset of this insulin and increases its duration.  (NPH stands for Neutral Protamine Hagedorn.  Hans Hagedorn was one of the inventors of NPH.)

OK, now to the good part.  "Protamine" comes from the "semen" (or "sperm") of Trout fish.  There is no known case of any female (or male) Type 1 on NPH giving birth to a  "Troutmen," which I guess would be the appropriate name for a trout - human designer hybrid :)

 

You're good Paul.

Here's a good. What company made the first glucose meter that used a bio-sensor (Clark Electrode)??? Hint: Yea USA

 Banting, Best and McCloud removed  the pacreas of a dog named Margery in 1921, watched it's health decline, and then injected her with ground cow pancreas. The first human to recieve the injection was a 13 year old boy named Leonard Thompson, who died of complications from years of untreated Diabetes at the age of 27. Though insulin was first discoverd in 1921, it was not mass produced until 1923 by eli lilly. Thank you Diabetes camp medical lectures : )