Big Bro needs help!

Both my brother and I have type 1. My brother has Asperger's and since his diagnosis in 2005, his world has been turned upside-down. His numbers consume his life. He has not had a job since he was diagnosed. Since he has such a gap in his resume, he has decided to volunteer. However, he is having a hard time securing a volunteer position.

How can someone with Asperger's enter the work / volunteer world? Meaning, do you communicate about your circumstance up-front? How do you introduce yourself?